only legal injection site in north america, a center that's come under fire from canada's conservative government. i asked dr. matÉ to talk about his patients. >> the hardcore drug addicts that i treat, but according to all studies in the states, as well, are, without exception, people who have had extraordinarily difficult lives. and the commonality is childhood abuse. in other words, these people all enter life under extremely adverse circumstances. not only did they not get what they need for healthy development, they actually got negative circumstances of neglect. i don't have a single female patient in the downtown eastside who wasn't sexually abused, for example, as were many of the men, or abused, neglected and abandoned serially, over and over again. and that's what sets up the brain biology of addiction. in other words, the addiction is related both psychologically, in terms of emotional pain relief, and neurobiological development to early adversity. >> what does the title of your book mean, in the realm of hungry ghosts? >> well, it's a buddhist phrase. in the buddhists' psychology, t